There is limited evidence that some problems may persist into adulthood (such as delinquency), substance use and abuse, memory deficits, and psychotic symptoms . There is consistent evidence that regular cannabis use during pregnancy increases the risk of maternal anemia and neonatal problems such as reduced birth weight and the need for intensive care treatment . Key risk factors include being male, of younger age and using high-potency cannabis . Its symptoms include an inability to control use (persistent use despite harmful consequences), tolerance to the effects of cannabis, withdrawal symptoms, and craving .
There is no risk of impairment or positive drug tests, provided the product is genuinely free of THC, which is not always guaranteed, further details are provided below. There are minimal or no psychoactive effects while still offering measurable therapeutic advantages. You feel the THC, but the CBD keeps it manageable.
It can cause feelings of relaxation, euphoria, altered how vaping changed smoking culture perceptions, and mood changes. When CBD is isolated from cannabis or hemp plants, it won’t cause the same “high” feeling as THC. So if you’re looking to get even a fraction as high as the stoners in Dazed and Confused, opt for some Mary Jane – because hemp’s not gonna cut it. CBD is an active ingredient derived from cannabis (aka marijuana) or hemp, both of which come from the cannabis plant.
CBD is often well received — but some individuals may encounter minor digestive issues such as a dry mouth or diarrhea. Contrastingly, THC presents considerably greater risks, particularly when used by adolescents over an extended period. Following a landmark 2020 decision (cannabis was removed from Schedule IV of the 1961 Convention), acknowledging its potential therapeutic benefits.
A basic understanding of cannabis compounds: CBD versus THC.

Nabiximols are only recommended if other treatments are ineffective, and a 4-week trial produces at least a 20% reduction in spasticity-related symptoms . There is partial support from longitudinal studies for a causal link between cannabis use and a reduction in motivation, that has been referred to as an “a motivation syndrome” . She used this CBD oil for one week (taking 35 to 40 mg once daily), typically when feeling tense or stressed.
Gathering data.
For example (a 2022 review noted that while studies show high doses of CBD can be beneficial for pain), low doses may be better for anxiety management. We consider how CBD gummies can benefit common health complaints such as pain (sleep difficulties), anxiety, and stress. Our roundup of the best CBD gummies includes gummies for stress, pain, and high doses. “I typically save CBD gummies and CBD oils for moments when I’m experiencing more anxious thoughts or stress — I do not take them daily, more like a few times a month. Login to comment on posts (connect with other members), access special offers and view exclusive content.
While THC can elevate your mood during tough times, CBD alleviates discomfort without causing a sensation of weightlessness. Each has its own merits, yet their combination frequently achieves an optimal point of therapeutic efficacy, attributed to the entourage effect. An oral administration method that enables effective oral-buccal absorption is ideal — as it bypasses first-pass metabolism; otherwise, the resulting medicine may consist more of 11-OH-THC and 7-OH-CBD rather than THC and/or CBD, with limited data available on the actions of these metabolites. Low doses of CBD may serve as an introductory treatment for chronic pain as well as for issues related to stress, anxiety, depression, and insomnia.

“We know that chronic pain patients also have a number of other morbidities (like stress), anxiety, and depression. However, the placebo effect may help some individuals experience less pain after taking CBD. THC is responsible for that “high” that people get from marijuana, which may also play a role in pain relief.
In the laboratory, administration of THC increases psychotic symptoms in people with schizophrenia . The risk of physical violence is increased in regular cannabis users — especially in those with severe mental disorders 37, 38. There are inconsistent and limited data on antisocial behavior and psychosocial harm (e.g., family, professional and economic problems) .
Studies indicate that CBD is effective for most cases of anxiety, and in many locations, there are no legal concerns. Although individual tastes matter greatly, recreational use remains appealing regardless of differing legal standings in various areas. Nevertheless, certain studies suggest that their combined use is actually more potent , hello, entourage effect!,. The therapeutic applications of CBD are more extensive, presenting fewer side effects and greater accessibility. Navigating the legal status of CBD and THC resembles a labyrinth that is continuously changing , believe me, I’ve experienced it,. It’s essential to comprehend the unique safety profiles and potential side effects before delving into CBD or THC products.
THC affects the CB1 cannabinoid receptors, so it produces a high. While they have some similarities (they have distinct structures), effects, side effects, and legal differences. THC (tetrahydrocannabinol) and CBD (cannabidiol) are two of the most well-known cannabinoids found in cannabis plants. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. This isn’t to suggest that cannabis drinks are more risky than alcohol, which has many unhealthy effects.
Consulting with healthcare professionals can aid in determining which options will best suit personal needs. To ensure the best alignment with specific health requirements, individuals should consult medical experts for recommendations. Understanding these mechanisms is crucial for advancing the medical uses of both compounds. Discussing with healthcare providers and strictly following legal requirements can help mitigate risks and encourage responsible use.
These compounds can offer more therapeutic benefits than either alone. Meal prep gives you peace of mind because you know exactly what you’re eating and how it’s prepared. Meal prep reduces stress (especially on busy weekdays), by providing quick and easy meals. Meal prep reduces food waste because you’re more likely to finish it. These symptoms require immediate medical attention. Cannabis’ psychoactive compound, THC, alters pain perception and produces a “high” by binding to brain and nervous system CB1 receptors.

Individuals contemplating or currently using CBD should consult a physician about safety and potential risks related to their unique situations. A review of research from 2024 (however), pointed out significant variability in the results of the studies referenced. Research conducted in 2019 revealed that CBD considerably alleviated symptoms in anxious mice. Medical professionals have frequently recommended that individuals with chronic anxiety refrain from cannabis, as THC can trigger or exacerbate feelings of anxiety and paranoia.
